Dystonia Think Tank

The 2026 Dystonia Think Tank meeting, hosted by the Norman Fixel Institute for Neurological Diseases and Tyler’s Hope for a Dystonia Cure, will take place in Gainesville, FL on April 24. This annual event brings together researchers and clinicians who work on dystonia to explore cutting-edge scientific discoveries, develop innovative therapeutic strategies, and enhance interdisciplinary care models.


Breakfast: 7:00-8:00 AM


Headshot of Yuquing Li, Ph.D.

8:00–10:00 AM

Basic Science Session

Session Moderator: Yuqing Li, Ph.D.

Session speaker

Mohammad Moshahid Khan, Ph.D

Title: Beyond the Gene: Microbiome Contributions to DYT1 Dystonia Pathobiology

Headshot of Mohammad Moshahid Khan, Ph.D

session speaker

Hyder (Buz) Jinnah, M.D., Ph.D.

Title: Human Induced Pluripotent Stem Cells for Inherited Dystonias

Headshot of Hyder (Buz) Jinnah, M.D., Ph.D.

session speaker

Meike van der Heijden, Ph.D.

Title: Cerebellar Signals in Dystonia

Headshot of Meike van der Heijden, Ph.D.
Headshot of Aparna A Wagle Shukla, M.D.

10:30 AM–12:30 PM

Clinical Session

Session Moderator: Aparna Wagle Shukla, M.D.

Session Speaker

Nutan Sharma, M.D., Ph.D.

Title: Biomarkers in Genetics forms of Dystonia

Headshot of Nutan Sharma, M.D., Ph.D.

session speaker

Michael Kruer, M.D.

Title: Potential utility of local field potentials in DBS for early-onset dystonia

Headshot of Michael Kruer, M.D.

session speaker

Ian Bledsoe, M.D.


Lunch: 12:30-1:30 PM


Headshot of Mark S Moehle, Ph.D.

1:30–3:30 PM

Gene Therapy Session

Session Moderator: Mark Moehle, Ph.D.

Session Speaker

Koen Breyne, Ph.D.

Title: Therapeutic Genome Editing for Genetic Dystonia

Koen Breyne, Ph.D.

session speaker

Christian Schlieker, Ph.D.

Title: Aberrant Phase Transitions in DYT1 Dystonia

Headshot of Christian Schlieker, Ph.D.

session speaker

Nicole Calakos, M.D., Ph.D.

Title: In search of disease-modifying treatments for dystonia: Update on efforts to develop small molecule ISR modulators

Headshot of Nicole Calakos, M.D., Ph.D.
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