This study aims to advance clinical care, research and therapeutic approaches in Friedreich’s ataxia (FA) through the development and validation of clinical outcome measures in FRDA, collection of quantitative serial clinical data on patients and expansion of our established research network.

To advance clinical care, research and therapeutic approaches in Friedreich’s ataxia (FA) through the development and validation of clinical outcome measures in FA, collection of quantitative serial clinical data on patients and expansion of our established research network.

The purpose of this research study is to find out what the best tests and evaluations are for measuring the effects of Friedreich’s ataxia on the body, to help us to design clinical trials.

This 2-part study will evaluate the efficacy, safety, and pharmacodynamics of omaveloxolone (RTA 408) in the treatment of patients with Friedreich’s ataxia.

The purpose of this study is to compare the efficacy of Troriluzole (200mg once daily) versus placebo after 48 weeks of treatment in subjects with spinocerebellar ataxia (SCA).

The investigators plan to fill the gap between the current state of clinical trial readiness and the optimal one for SCA1 and SCA3, which are fatal rare diseases with no treatments.

The purpose of this research study is to bring together a group of experts in the field of SCA for the purpose of learning more about the disease.

he primary purpose of this study is to compare the efficacy of BHV-4157 versus placebo after 8 weeks of treatment on ataxia symptoms in subjects with spinocerebellar ataxia (SCA).

Researchers want to find out if daxibotulinumtoxinA for injection, a new investigational study drug, is safe and effective for use in adults with isolated cervical dystonia (CD) and if the effects last longer than the standard toxin treatment.

The purpose of this research study is to collect clinical information about you and your health. We will also collect biological samples, such as blood and DNA (the genetic material in your blood). Researchers will use this information and samples to learn more about Huntington’s disease and to try to find new treatments for the disease

The purpose of this study is to learn more about the effects of treatment with IPT803 on Parkinson’s disease symptoms and how it impacts your daily life.

The purpose of this research is to collect blood from Parkinson’s disease patients and healthy individuals, as well as patients with major depressive disorder and Alzheimer’s disease, of the same age or gender as those patients in the hope to find future diagnostics tools and establish early therapeutic biomarkers for Parkinson’s disease.

This study determines a baseline for leaky gut for people with Parkinson’s disease (PD) versus healthy controls. We also hope to see if eating a Mediterranean diet will alter gut, bacteria, inflammation, and function in people with PD.

The purpose of this research study is to collect data on individuals with Parkinson disease to better understand the illness and ultimately improve the care and survival of those individuals with the disease.

We are recruiting individuals with Parkinson disease for a new brain stimulation study that involves ‘shining’ light on the brain.

The purpose of this research study is to investigate how the brain and motor behavior changes Parkinson’s disease over time in response to rasagiline and to investigate new methods of evaluating non-invasive MRI-based biomarkers of PD progression in the brain.

The purpose of this research study is to investigate how the brain and motor behavior changes both in individuals with movement disorders and healthy individuals over time.

The purpose of this study is to validate a malnutrition screening tool in patients with Parkinson’s disease.

This study will help us to better understand swallowing impairment and how liquid thickness influences swallowing function.

The purpose of this research study is to investigate 1) brain and blood markers of memory and thinking difficulties in Parkinson’s disease, and 2) how these markers can predict different memory and thinking difficulties over a period of two years. Individuals diagnosed with Parkinson’s disease are being compared to individuals who do not have Parkinson’s disease.

The purpose of this research is to improve the identification of patients who are at greater risk for development of dysphagia (dys FAY juh – swallowing difficulties) after cardiac surgery.

The purpose of this research is to assess how useful a Virtual Reality program is in assisting and enhancing the ability of adults to experience and choose appropriate home modifications for themselves.

The purpose of this additional research study is to determine whether LY3154207 has an effect on your blood pressure and pulse rate during normal activities, especially while you are asleep at night.

The goal of this study is to store your tissues and medical information and potentially use it in future research.

The purpose of this research study is to determine the effects of Deep Brain Stimulation (DBS) on gut health in patients with Pakinson’s disease (PD) and without Parkinson’s disease (this is the control group).

If your child (ages 6-16) have been diagnosed with Tourette syndrome you may be eligible to take part in a research study of an experimental drug called TEV-50717, which is being developed as a treatment for tics associated with Tourette syndrome in children and adolescents.

The purpose of this research study is to determine if we can use muscle activity to detect tics involving the arms, legs and back.

The purpose of this research study is to better understand if there are handwriting changes and patterns associated with Tourette syndrome and tic disorders.

We wish to store your medical information and routine completed questionnaires to potentially use it in future research. Many different kinds of research uses medical information from data bank sources.

The purpose of this study is to learn how deep brain stimulation affects motor and vocal tics associated with severe Tourette Syndrome that is not adequately controlled with medication.

The purpose of this research study is to test the effectiveness and safety of Responsive Deep Brain Stimulation (R-DBS) for Essential Tremor (ET). Current DBS therapy for ET leaves the device on all of the time, even when you do not have tremor.